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Rabeprazole
Clinical data
Pronunciation/ r ə ˈ b ɛ p r ə ˌ z ɔː l /
Trade namesAcipHex, others
AHFS/Drugs.comMonograph
MedlinePlusa699060
License dataUS   FDA: Rabeprazole
Pregnancy categoryUS: C [1]
Routes of administrationby mouth
Drug classproton pump inhibitor [2]
ATC codeA02BC04 ( WHO )
Legal status
Legal statusUK: POM (Prescription only) US: ℞-only
Pharmacokinetic data
Bioavailability52% [2]
Protein binding96.3% [3]
MetabolismCYP2C19 and CYP3A4 in the liver [2]
Metabolitesthioether carboyxlic acid metabolite, thioether glucuronide metabolite, sulfone metabolite [3]
Elimination half-life~1 hour [2]
Excretion90% via kidney as metabolites [4]

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