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Clinical data | |
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Trade names | Cataflam, Voltaren, see trade names [1] |
AHFS/Drugs.com | Monograph |
MedlinePlus | a689002 |
Pregnancy category | AU: C US: C (Risk not ruled out) in 1st and 2nd trimester, D in 3rd trimester |
Routes of administration | oral, rectal, intramuscular, intravenous (renal- and gallstones), topical |
ATC code | D11AX18 ( WHO ) M01AB05 ( WHO ), M02AA15 ( WHO ), S01BC03 ( WHO ) |
Legal status | |
Legal status | AU: S2 (Pharmacy only) – S4, UK: POM (Prescription only) (P for topical formulation), ℞-only in most preparations/countries, limited OTC in some countries, manufacture and veterinary use is banned in India, Nepal, and Pakistan due to imminent extinction of local vultures |
Pharmacokinetic data | |
Protein binding | More than 99% |
Metabolism | hepatic, oxidative, primarily by CYP2C9, also by CYP2C8, CYP3A4, as well as conjugative by glucuronidation (UGT2B7) and sulfation; [2] no active metabolites exist |
Elimination half-life | 1.2–2 hr (35% of the drug enters enterohepatic recirculation) |
Excretion | 40% biliary 60% urine |
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Diclofenac information | |
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Tablet name | diclofenac |
Active substance | diclofenac, diclofenac |
Best price | $39.38 per dose |
Besteller | 90 tablets x 100 mg |
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Use as directed Diclofenac is used for short-term treatment. No more than 16 grams per day should be used for any single joint of the knee, ankle or foot.
Your medication may not work as well or may stop working completely. If your doctor wants you to use it for a longer time, your doctor should check your liver function, kidney function, and blood pressure periodically – diclofenac topical (osteoarthritis pain).
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Always speak with your doctor or pharmacist about dosages that are right for you. Keep it in your carry-on bag.
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Our team works directly with over U. As part of a complete therapy plan, Americans taking Voltaren Gel may experience relief from the symptoms of their condition, including pain or can diclofenac cause liver damage.
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