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Dapoxetine
Clinical data
Trade namesPriligy, others (see below)
AHFS/Drugs.comInternational Drug Names
Routes of administrationOral (tablets)
ATC codeG04BX14 ( WHO )
Legal status
Legal statusIn general: ℞ (Prescription only)
Pharmacokinetic data
Bioavailability15–76% (mean 42%), T max = 1–1.3 hours
Protein binding>99%
MetabolismLiver (CYP2D6, CYP3A4), kidney (FMO1)
MetabolitesDapoxetine- N -oxide, desmethyldapoxetine, didesmethyldapoxetine
Elimination half-life1.5–1.6 h
ExcretionKidneys [1]

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Hereby, closely monitor your health conditions during the treatment with Priligy and consult with your doctor in case of any anomalies. These include men with a history of low blood pressure and symptoms caused by falls in blood pressure, such as dizziness and blackouts when standing. Do not take daily on a regular basis, or repeat a dose within 24 hours.


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Priligy is not allowed for prescription to women. Men with heart disease and significant liver or kidney disease should not take Priligy, without first consulting their doctors.


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The dose can be increased to one 60mg tablet, as required, providing the 30mg dose has been well tolerated no significant side effects are experienced.


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Priligy is not advised to be taken for a continuous daily use. The risk of adverse cardiovascular results from syncope increase among patients suffering from underlying structural cardiovascular disease e.


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National Council on Aging. Do not stop prescribed medicine without first consulting a doctor or pharmacist.


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