Metformin (metformin, metformin) 500 mg, approximately 1 hour before sexual activity.
Metformin patients should be stable on alpha-blocker therapy prior to initiating treatment and should be initiated at 25 mg. The recommended dose is 50 mg.
Clinical data | |
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Pronunciation | / m ɛ t ˈ f ɔːr m ɪ n /, met- FAWR -min |
Trade names | Glucophage, other |
AHFS/Drugs.com | Monograph |
MedlinePlus | a696005 |
License data | EU EMA: by INN, US FDA: metformin |
Pregnancy category | AU: C US: B (No risk in non-human studies) |
Routes of administration | by mouth |
ATC code | A10BA02 ( WHO ) |
Legal status | |
Legal status | AU: S4 (Prescription only) CA : ℞-only UK: POM (Prescription only) US: ℞-only |
Pharmacokinetic data | |
Bioavailability | 50–60% [2] [3] |
Protein binding | Minimal [2] |
Metabolism | Not by liver [2] |
Elimination half-life | 4–8.7 hours [2] |
Excretion | Urine (90%) [2] |
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Metformin information | |
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Tablet name | metformin |
Active substance | metformin, metformin |
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