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Nicotinell (nicotine, nicotine) 18 mg, in the presence of sexual stimulation.

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Nicotine
Clinical data
Trade namesNicorette, Nicotrol
AHFS/Drugs.comMonograph
Pregnancy categoryAU: D US: D (Evidence of risk)
Dependence liabilityPhysical: low–moderate Psychological: moderate–high [1] [2]
Addiction liabilityHigh [3]
Routes of administrationInhalation; insufflation; oral – buccal, sublingual, and ingestion; transdermal; rectal
ATC codeN07BA01 ( WHO ) QP53AX13 ( WHO )
Legal status
Legal statusAU: Unscheduled CA : Unscheduled DE : Unscheduled NZ : Unscheduled UK: Unscheduled US: Unscheduled UN: Unscheduled
Pharmacokinetic data
Protein binding<5%
MetabolismPrimarily hepatic: CYP2A6, CYP2B6, FMO3, others
MetabolitesCotinine
Elimination half-life1-2 hours; 20 hours active metabolite
ExcretionUrine (10-20% (gum), pH-dependent; 30% (inhaled); 10-30% (intranasal))
NFPA 704 fire diamond
1 4 0
The fire diamond hazard sign for nicotine with synthroid and calcium. [112]

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Nicotinell information
Drug name nicotinell
Nicotinell synonym ,,,
Active substance nicotine, nicotine
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Besteller 1 tablets x 18 mg
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